On-demand and unpublished lectins

On-demand lectins:

Upon request, 4GLYCO can prepare additional lectins from the list below. Contact us at contact@4glyco.cz for prices and availability of the products.

• BC2L-C, C-terminal domain - Ca²⁺-dependent, mannose-specific lectin from Burkholderia cenocepacia with a preference to oligoMan structures [1]
• CV-IIL - Ca²⁺-dependent lectin from Chromobacterium violaceum which binds d-mannose and l-fucose with almost equal affinities [2]
• RS-IIL - Ca²⁺-dependent, mannose-specific lectin from Ralstonia solanacearum [3]

References:

1. Šulák et al, PLoS Pathog, 2011, doi: 10.1371/journal.ppat.1002238
2. Pokorná, Cioci et al, Biochemistry, 2006, doi: 10.1021/bi060214e
3. Sudakevitz, Kostlánová et al, Mol Microbiol, 2004, doi: 10.1111/j.1365-2958.2004.04020.x

Unpublished lectins:

4GLYCO can mediate access to novel lectins currently studied in the Michaela Wimmerová research group. These lectins are free of charge and available for research collaboration. However, please note that they are not subjected to the same quality control as 4GLYCO lectins, and no certificate of analysis is provided for them.

Available unpublished lectins:

• fungal lectin specific to complex-type N-glycans
  
• bacterial lectin with a preference for β-galactosides
• bacterial glycosaminoglycan-specific lectin recognizing hyaluronic acid and heparan sulfate

If you are interested in these lectins, contact us at contact@4glyco.cz.